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正交试验优选苦参生物碱提取工艺研究

王丹 吕佳 张振秋 赵琳

中国中医药信息杂志2011,Vol.18Issue(1):51-52,2.
中国中医药信息杂志2011,Vol.18Issue(1):51-52,2.DOI:10.3969/j.issn.1005-5304.2011.01.020

正交试验优选苦参生物碱提取工艺研究

Orthogonal Optimization of Extraction Process of Sophora Alkaloid

王丹 1吕佳 1张振秋 1赵琳1

作者信息

  • 1. 辽宁中医药大学药学院,辽宁,大连,116600
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摘要

Abstract

Objective To optimize the extraction process of Sophora alkaloids in Sophora flavescens Ait. by orthogonal design. Methods The optimum extraction condition was investigated by orthogonal design and the extraction quantity of matrine and oxymatrine was regarded as the investigated index. Results The optimal extraction process was as follows: refluxing herbs for 3 times with 12, 10, 10 times of 60% alcohol, two hours for each time. Conclusion The optimized process is stable and suitable for industrial manufacture.

关键词

苦参/苦参生物碱/氧化苦参碱/苦参碱/提取工艺/正交试验

分类

中医学

引用本文复制引用

王丹,吕佳,张振秋,赵琳..正交试验优选苦参生物碱提取工艺研究[J].中国中医药信息杂志,2011,18(1):51-52,2.

基金项目

大连市科技局科学技术基金(2008J21JH007) (2008J21JH007)

中国中医药信息杂志

OACSCDCSTPCD

1005-5304

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