中国药业2011，Vol.20Issue(3)：14-15,2.
高效液相色谱法测定生物黏附剂中辛苯醇醚含量
Determination of Octoxynol-9 in Biological Adhesive by HPLC
刘苗苗 1赵齐 2沈丽琳1
作者信息
- 1. 天津市计划生育研究所,天津,300191
- 2. 天津大学化学工程联合国家重点实验室,天津,300072
- 折叠
摘要
Abstract
Objective To establish a content determination method of octoxynol-9 in biological adhesive for external use by HPLC. Methods The Shimadzu VP-ODS chromatographic column(250 mm ×4.6 mm, 5 μm) was adopted with the mobile phase of methanol-water(90∶10)and the flow rate of 1.0 mL/min. The detecting wavelength was 276 nm. Results The calibration curves were linear within the range of 1.02 - 24.48 μg( r = 0.999 6). The average recovery rate was 99.06％, RSD was 1.14％ ( n = 6). Conclusion The method is sensitive,accurate, rapid and reproducible, which can be used for the determination of octoxynol- 9 in biological adhesive for external use.关键词
高效液相色谱法/生物黏附剂/辛苯醇醚/含量测定分类
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刘苗苗,赵齐,沈丽琳..高效液相色谱法测定生物黏附剂中辛苯醇醚含量[J].中国药业,2011,20(3):14-15,2.
