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松针叶绿素-胡萝卜素软膏对实验性胃溃疡的防治作用

郑光耀 李骄 薄采颖 李海涛 宋强

林产化学与工业2011,Vol.31Issue(1):26-30,5.
林产化学与工业2011,Vol.31Issue(1):26-30,5.

松针叶绿素-胡萝卜素软膏对实验性胃溃疡的防治作用

Effects of Chlorophyll-carotene Paste from Pine Needles on Experimental Gastric Ulcer

郑光耀 1李骄 2薄采颖 1李海涛 2宋强1

作者信息

  • 1. 中国林业科学研究院林产化学工业研究所,生物质化学利用国家工程实验室,国家林业局林产化学工程重点开放性实验室,江苏南京,210042
  • 2. 南京中医药大学药学院,江苏南京,210046
  • 折叠

摘要

Abstract

Gastritis models induced by pyloric ligation, ethanol and acetic acid in rats were used to investigate the anti-gastric ulcer action of chlorophyll-carotene paste from pine needles. The gastric ulcer area, gastric juice quantity, pH value, pepsin activity were measured and pathological slices were examined. The results showed that chlorophyll-carotene paste from pine needles groups with different dosages of 0.75, 1.50 and 2.25 g/kg inhibited gastric secretion, increased gastric juice pH value and decreased pepsin activity remarkably ( P < O. 01 ), It also greatly inhibited the formation of gastric ulcers induced by pyloric ligation,ethanol and acetic acid(P <0.01 ). The inhibitory rates at the dosage of 2.25 g/kg were 84.39 %, 65.33 % and 80.68 % respectively. It was seen that Chlorophyll-carotene paste from pine needles had preventive and therapeutic effects on experimental gastric ulcer.

关键词

松针/叶绿素-胡萝卜素软膏/胃溃疡

Key words

pine needles/ chlorophyll-carotene paste/ gastire ulcer

分类

化学化工

引用本文复制引用

郑光耀,李骄,薄采颖,李海涛,宋强..松针叶绿素-胡萝卜素软膏对实验性胃溃疡的防治作用[J].林产化学与工业,2011,31(1):26-30,5.

基金项目

科技部农业科技成果转化资金项目(2008GB24320412) (2008GB24320412)

林产化学与工业

OA北大核心CSCDCSTPCD

0253-2417

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