实用临床医药杂志2011，Vol.15Issue(3)：81-82,85,3.
盐酸帕洛诺司琼在乳腺癌化疗中的止吐疗效观察
The antiemetic efficacy of palonosetron hydrochloride in breast cancer chemotherapy
李曦洲 1隋金珂 1施俊义1
作者信息
- 1. 第二军医大学附属长海医院,甲乳外科,上海,200433
- 折叠
摘要
Abstract
Objective To explore the effect of Palonosetron in preventing nausea and vomiting induced by TEC chemotherapy regimen for breast cancer. Methods Eighty- four cases of breast cancer following modified radical mastectomy were randomly divided into Palonosetron group ( n = 42) and Tropisetron group ( n = 42). Both received TEC regimen for the first time. The degree and frequency of nausea and emesis were observed in 72 hours. Results The effectiverate of Palonosetron and Tropisetron was respectively 92.9％ and 71.4％, which weres significantly different(P ＜ 0.05). In 24 hours, there was no statistical difference between two groups(P ＞0.05). In 48 and 72 hours, the effect of Palonosetron group was better than Tropisetron group(P＜0.05).Conclusion Palonosetron is an ideal long - acting antiemetic drug which can effectively prevent chemotherapy- induced vomiting and nausea.关键词
盐酸帕洛诺司琼/乳腺癌/化疗/止吐分类
医药卫生引用本文复制引用
李曦洲,隋金珂,施俊义..盐酸帕洛诺司琼在乳腺癌化疗中的止吐疗效观察[J].实用临床医药杂志,2011,15(3):81-82,85,3.
