重庆医学2011，Vol.40Issue(8)：749-751,后插1,4.DOI:10.3969/j.issn.1671-8348.2011.08.009
18F-FDG PET/CT、CA19-9对胰腺癌的诊断价值
Diagnostic value of 18F-FDG PET/CT and CA19-9 in pancreatic cancer
摘要
Abstract
Objective To discuss the diagnostic value of 18 F-fluorodeoxyglucose(18 F-FDG) PET/CT and CA19-9 in pancreatic cancer. Methods 55 patients with space-occupying lesions of the pancreas confirmed by B ultrasound,CT or MRI were selected for this study. Whole body 18 F-FDG PET/CT scanning was performed and the level of serum CA19-9 was measured. Results Among 55 patients with space-occupying pancreatic lesions,35 patients were diagnosed as pancreatic cancers, and other 20 patients as benign diseases. The values of mean SUV and CA19-9 were significantly different between pancreatic cancers and benign diseases(t= 3. 543 ,P = 0. 001 ,t = 2. 211 , P = 0. 034 ) respectively. The sensitivity, specificity, positive and negative predictive value, accuracy of is FDG PET/CT was, respectively, 97. 1 ％ ,80. 0 ％ , 89. 5％ , 94. 1 ％ and 90. 9 ％. The diagnostic value of CA19-9 was lower than that of 18 F-FDG PFT/CT, while combined application the diagnosis specificity increased to 90. 0％ , with only a slight decreasing in diag nosis accuracy(87. 3％). Conclusion 18 F-FDG PET/CT has high sensitivity in diagnosis of pancreatic cancer and relative specificity,whtch would increase the diagnosis specificity combined with CA19-9.关键词
氟脱氧葡萄糖F18/正电子发射断层摄影术/糖类抗原19-9/X线计算机引用本文复制引用
池晓华,王全师,李贵平,吴湖炳..18F-FDG PET/CT、CA19-9对胰腺癌的诊断价值[J].重庆医学,2011,40(8):749-751,后插1,4.基金项目
国家自然科学基金资助项目(81071174). （81071174）
