中国当代儿科杂志2011，Vol.13Issue(1)：20-22,3.
儿童支气管肺炎革兰阴性菌耐药监测分析
Antibiotic resistance of gram-negative Bacillis isolated from children with bronchopneumonia
韦鸿雁 1谭波宇 2杨丽君 1邓楠1
作者信息
- 1. 湖南省人民医院药学部临床药学办,湖南长沙410002
- 2. 湖南师范大学医学院药学系,湖南长沙410005
- 折叠
摘要
Abstract
Objective To study the distribution and antibiotic resistance of gram-negative pathogens isolated from children with bronchopneumonia. Methods The distribution and the results of susceptibility tests of 272 strains of gramnegative Bacillis isolated from children with bronchopneumonia during 2009 were analyzed. Results Among the isolates, the common pathogens were Klebsiella pneumoniae and Escherichia coli. The extended-spectrum β-1actamase (ESBLs) production rate was 52.9％. Compared with the non-ESBLs producing strains, ESBLs-producing strains had a significantly higher drug resistance rate to many antibiotics except amikacin and meropenem ( P ＜ 0. 05 ). The lowest resistance to ESBLs producing gram negative strains was found for meropenem (0.7％), followed by imipenem, amikacin and cefoperazone/sulbactam. Conclusions More attentions should be paid to the high rate of drug-resistance of ESBLs producing strains in children. Antimicrobial therapy should be based on the results of drug resistance surveillance.关键词
革兰阴性菌/支气管肺炎/耐药/儿童分类
医药卫生引用本文复制引用
韦鸿雁,谭波宇,杨丽君,邓楠..儿童支气管肺炎革兰阴性菌耐药监测分析[J].中国当代儿科杂志,2011,13(1):20-22,3.
