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What is the optimal initiation timing of angiotensin converting enzyme inhibitor treatment for maximum benefits in acute myocardial infarction patients?

YAN Hong-bing WANG Shao-ping

中华医学杂志(英文版)2011,Vol.124Issue(3):464-466,3.
中华医学杂志(英文版)2011,Vol.124Issue(3):464-466,3.DOI:10.3760/cma.j.issn.0366-6999.2011.03.026

What is the optimal initiation timing of angiotensin converting enzyme inhibitor treatment for maximum benefits in acute myocardial infarction patients?

What is the optimal initiation timing of angiotensin converting enzyme inhibitor treatment for maximum benefits in acute myocardial infarction patients?

YAN Hong-bing 1WANG Shao-ping2

作者信息

  • 1. Coronary Heart Disease Center, Cardiovascular Institute and Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China
  • 2. The 28th Division, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China
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摘要

Abstract

Randomized clinical trials led to the clinical recommendation that angiotensin-converting enzyme inhibitors (ACEI) should be used as standard therapy in most patients experiencing an acute myocardial infarction (AMI). However, the optimal initiation timing of treatment, as well as the exact mechanisms, have not been completely resolved, especially with the development of reperfusion strategy after AMI. Earlier initiation of ACEI might be associated with more prompt recovery of left ventricular ejection fraction due to more rapid attenuation of negative remodeling.

关键词

angiotensin-converting enzyme inhibitor/acute myocardial infarction/left ventricular remodeling

Key words

angiotensin-converting enzyme inhibitor/acute myocardial infarction/left ventricular remodeling

引用本文复制引用

YAN Hong-bing,WANG Shao-ping..What is the optimal initiation timing of angiotensin converting enzyme inhibitor treatment for maximum benefits in acute myocardial infarction patients?[J].中华医学杂志(英文版),2011,124(3):464-466,3.

基金项目

This work was supported by a grant from the Science and Technology Development Fund of Anzhen Hospital President. ()

中华医学杂志(英文版)

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