重庆医学2011，Vol.40Issue(4)：355-356,358,3.DOI:10.3969/j.issn.1671-8348.2011.04.019
CA153、IL-6及IL-8与乳腺癌骨转移相关性探讨
Study on the correlation between CA153, IL-6, IL-8 levels and bone metastasis in patients with breast cancer
杨士军 1谭维琴 1鲍艳梅1
作者信息
- 1. 南京医科大学附属淮安第一医院核医学科,江苏,223300
- 折叠
摘要
Abstract
Objective To investigate the corelation of CA153,IL-6,IL-8 and breast cancer bone metastasis. Methods 103 breast cancer patients after radical surgery were scanned by single photon emission computer tomography(SPECT). Immunoradiometric assay(IRMA) method was used to assay the serum.level of CA153,and radioimmunoassay(RIA) method was used to assay serum level of IL-6,IL-8;At the same time,the result was analyzed against the control group of 36 normal people. Results In breast cancer patients group with bone metastasis, the serum level of CA153, IL-6, IL-8 were significantly higher than normal people(P＜0.05) ,while the serum level of CA153,IL-6 and IL-8 in cancer patients group without bone metastasis and in control group were not statistically significant different(P＞0.05). Conclusion CA153 has great significance in predicting breast cancer bone metastasis and screening whole body bone imaging;IL-6, IL-8 is engaging in the occurrence and development of bone metastasis, assaying the serum levels of IL-6,IL-8 are of great value to pathology research,prevention and treatment of breast cancer bone metastasis.关键词
乳腺肿瘤/白细胞介素6/白细胞介素8/糖类抗原CA153Key words
breast neoplasms/ interleukin 6 /interleukin 8/ carbohydrate antigen 153引用本文复制引用
杨士军,谭维琴,鲍艳梅..CA153、IL-6及IL-8与乳腺癌骨转移相关性探讨[J].重庆医学,2011,40(4):355-356,358,3.
