重庆医学2011，Vol.40Issue(11)：1044-1045,1048,3.DOI:10.3969/j.issn.1671-8348.2011.11.002
乳腺癌患者新辅助化疗对雌激素受体表达的影响
The effect of neo-adjuvent therapy on expression of estrogen receptor
摘要
Abstract
Objective To explore the relationship between estrogen receptor expression and treatment response induced by neoadjuvant therapy. Methods Biopsy tissue samples from 109 patients with primary breast cancer were tested for estrogen receptor expression by immunohistochemistry. Results Dramatically down regulated expression of estrogen receptor occurred in 13 cases,and up-regulated expression took place in 16 patients. The chemical-induced alteration of estrogen expression in breast cancer was not associated with the response of neo-adjuvant treatment. Conclusion The chemical-induced expression of estrogen could not be taken as a guideline for choice of adjuvant or hormone therapy in breast cancer patients.关键词
乳腺肿瘤/受体,雌激素/新辅助化疗Key words
breast neoplasms/ receptor, estrogen/ neo-adjuvant therapy引用本文复制引用
朱宁生,邱惠,吕钢,江歌丽..乳腺癌患者新辅助化疗对雌激素受体表达的影响[J].重庆医学,2011,40(11):1044-1045,1048,3.
