摘要
Abstract
Objective To summarize the methods of localization of epileptogenic focus and surgical treatment of medically refractory epilepsy. Methods All the 150 cases of refractory epilepsy patients were examined with preoperative axial coronal sagittal MRI,video EEG(VEEG) monitoring ,in which 20 cases PET-CT imaging of the brain;Epileptogenic zone was removed when patents in the cortical electroencephalogram (EcoG) monitoring, including 59 cases of partial resection of the epileptic focus, anterior temporal lobe and temporal lobe plus amygdala, hippccampus resection of 50 cases, selective amygdala, hippocampus resection in 3 cases,frontal lobe epileptic foci excision in 28 cases, frontal plus temporal lobe excision in 7 cases,3 cases of hemispherectomy. Results Lateralization and localization accuracy of epileptogenic focus of preoperative MRI,VEEG,and PET-CT was 70. 6％ ,83.5％ and 94.4％ respectively. Patients were followed up for 1.5 a,effect of grade Ⅰ ( Engel classification) in 57 cases, Ⅱ grade 52 cases, Ⅲ grade 33 cases, Ⅳ grade 8 cases. Conclusions The integrated application of imaging, EEG and radionuclide examination can more accurately locate the epileptic foci,the effects of resection of epileptogenic focus will be better in EcoG monitoring.关键词
难治性癫痫/定位方法/磁共振技术/视频脑电图/核素显像技术/皮质脑电图/外科手术Key words
medically refractory/ localization/ magnetic resonance imaging/ Video EEG/ radionuclide imaging/ cortical electroencephalogram/ EEG depth electrodes/surgical treatment分类
医药卫生
