中山大学学报（医学科学版）2011，Vol.32Issue(1)：76-80,5.
三种方法治疗围绝经期女性情绪障碍的比较
Comparison of Three Kinds of Regimens Dealing with Women Emotional Disorder during Perimenopause
摘要
Abstract
[Objective]To explore the best regimen dealing with perimenopausal women emotional disorder.[Methods]Sixtytwo perimenopausal women with emotional disorder screened by SAS and SDS were randomly registered into three different groups (20 for paroxetine combined with psychological therapy, 21 for paroxetine combined with hormone replace treatment and psychological therapy, 21 for hormone replace treatment combined with psychological therapy), and they accepted four weeks,observation.Every patient accepted the assessment of these rating scales (including Greene, HAMA, HAMD) one time before and after treatment, and only one test for TESS after treatment.[Results]All regimens improved the score of Greene and HAMA, but there was no statistical difference between different regimens.HRT combined with psychological therapy did not effectively improve the score of HAMD, Both paroxetine combined with psychological therapy and paroxetine combined with HRT and psychological therapy improve the score of HAMD much more than HRT combined with psychological therapy (P=0.018).There is no significant difference of TESS score between different regimens (P = 0.08).[Conclusion]considering that latent, far-reaching serious disadvantages, the regimen of paroxetine combined with psychological therapy deserves to be advocated in our clinical practice.关键词
围绝经期/情绪障碍/帕罗西汀/利维爱/激素替代疗法分类
医药卫生引用本文复制引用
吴小立,钟智勇,韩自力,王相兰..三种方法治疗围绝经期女性情绪障碍的比较[J].中山大学学报（医学科学版）,2011,32(1):76-80,5.基金项目
广东省医学科研基金项目(A2009199) （A2009199）
