重庆医学2011，Vol.40Issue(2)：131-132,2.DOI:10.3969/j.issn.1671-8348.2011.02.012
机械通气治疗COPD前后细胞因子IL-8、IL-13及IL-18的变化
The changes of IL-8, IL-13 and IL-18 in patients of COPD before and after the treatment of mechanical ventilation
李艳 1何家富1
作者信息
- 1. 湖北省襄樊市中心医院呼吸内科,441201
- 折叠
摘要
Abstract
Objective To study the expressions of IL-8 and IL-13 and IL-18 in patients of chronic obstructive pulmonary disease (COPD) before and after the treatment of mechanical ventilation. Methods The blood of thirty COPD before and after the treatment of mechanical ventilation at 1,2,6,72 h was collected in the period of exacerbation which needed invasive mechanical ventila tion. We also collected the blood of ten COPD in the period of stable stage. The expressions of IL-8 and IL 13 and IL-18 in the blood plasma were detected by enzyme linked immunosorbent assay(El.ISA). Results The expressions of IL-8 and IL-13 and IL-18 in the period of exacerbation were decreased obviously after the treatment of mechanical ventilation. Those expressions had no significantly difference between the COPD patients which needed the mechanical ventilation treatment by 72 h and the COPD patients in the period of stable stage. Conclusion The expressions of IL-8 and IL-13 and IL 18 in the period of exacerbation increase significantly and decrease obviously after the mechanical ventilation treatment.关键词
肺疾病,阻塞性/白细胞介素8/白细胞介素13/白细胞介素18/机械通气Key words
lung disease/obstructive/interleukin-8/ interleukin-13 /interleukin-18/ mechanical ventilation引用本文复制引用
李艳,何家富..机械通气治疗COPD前后细胞因子IL-8、IL-13及IL-18的变化[J].重庆医学,2011,40(2):131-132,2.
