癌症2011，Vol.30Issue(2)：106-113,8.
Nasopharyngeal carcinoma in the Northeastern states of India
Nasopharyngeal carcinoma in the Northeastern states of India
Amal Chandra Kataki 1Malcolm J. Simons 2Ashok Kumar Das 3Kalpana Sharma 4Narinder Kumar Mehra5
作者信息
- 1. Regional Institute for Cancer Treatment & Research, Dr. B. Borooah Cancer Institute, Guwahati, Assam 781016, India
- 2. Department of Experimental Research, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong 510060, P. R. China
- 3. Simons Haplomics Limited, Hong Kong SAR, P. R. China
- 4. Department of Head & Neck Oncology, Dr. B. Borooah Cancer Institute, Guwahati, Assam 781016, India
- 5. Department of Otolaryngorhinology, Gauhati Medical College, Assam, Assam 781016, India
- 折叠
摘要
Abstract
Nasopharyngeal cancer (NPC) is a rare disease in most parts of the world, except for Southeast Asia, some parts of North Africa and the Arctic. It is mostly seen in people of Chinese origin. In India, NPC is also rare, except for the Hill States of Northeast India, particularly Nagaland, Manipur, and Mizoram. The striking feature of NPC in Northeast India is that the incidence ranges over the complete spectrum from the lowest (as 0.5/100 000 to 2.0/100 000 among Caucasoid) to the highest (as ～20/100 000 among Cantonese/Zhongshan dialect Chinese). The age-adjusted rate of NPC in Kohima district of Nagaland State is 19.4/100000, which is among the highest recorded rates. By contrast, in Assam, one of the so called Hill States but not itself a hilly state, NPC is much less common. The Northeastem region is distinguished by a preponderance of the Tibeto-Burman languages and by variable mongoloid features among peoples of the region. The nature of the migratory populations who are presumed to be bearers of the mongoloid risk is unknown, but these NPC occurrence features provide an outstanding opportunity for NPC risk investigation, such as that of the hypothesis of Wee et al. for westward displacement of Chinese aborigines following the last glacial maximum.关键词
Nasopharyngeal neoplasm/ Northeast India/ age-adjusted rateKey words
Nasopharyngeal neoplasm/ Northeast India/ age-adjusted rate引用本文复制引用
Amal Chandra Kataki,Malcolm J. Simons,Ashok Kumar Das,Kalpana Sharma,Narinder Kumar Mehra..Nasopharyngeal carcinoma in the Northeastern states of India[J].癌症,2011,30(2):106-113,8.
