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钙调蛋白在PC12细胞分化和迁移中的作用

袁俊 李朝军

华北农学报2011,Vol.26Issue(1):22-25,4.
华北农学报2011,Vol.26Issue(1):22-25,4.

钙调蛋白在PC12细胞分化和迁移中的作用

Effect of Calmodulin on the Differrentiation and Migration of PC12 Cells

袁俊 1李朝军2

作者信息

  • 1. 南京晓庄学院,生物化工与环境科学学院,江苏,南京,211171
  • 2. 南京大学,医学院,江苏,南京,210093
  • 折叠

摘要

Abstract

To investigate the roles of calmodulin during neuronal differentiation and migration,we checked PC12 cells by immunofluorescence staining and single cell tracking assay after NGF treatment. We found that calmodulin showed a dense distribution pattern in top of PC12 cells. Only a small percentage of the cells grown in W7 treatment cells. A single cell tracking experiment showed that calmodulin in PC12 cells could increase cell motility. The data suggested that calmodulin may play an important role in differentiation and migration of PC12 cells.

关键词

钙调蛋白/PC12细胞/W7/分化/迁移

Key words

Calmodulin/ PC12 cell/ W7/ Differentiation/ Migration

分类

生物科学

引用本文复制引用

袁俊,李朝军..钙调蛋白在PC12细胞分化和迁移中的作用[J].华北农学报,2011,26(1):22-25,4.

华北农学报

OA北大核心CSCDCSTPCD

1000-7091

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