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腹泻患儿诺如病毒和轮状病毒感染96例临床特点分析

李克蓉 曹虹 周锦妍 汪艳 杨娟 黄永坤

昆明医学院学报2011,Vol.32Issue(1):86-89,4.
昆明医学院学报2011,Vol.32Issue(1):86-89,4.

腹泻患儿诺如病毒和轮状病毒感染96例临床特点分析

Cclinical Characteristics of Norovirus and Rotavirus Infection in 96 Children with Diarrhea

李克蓉 1曹虹 1周锦妍 1汪艳 1杨娟 1黄永坤2

作者信息

  • 1. 昆明医学院附属延安医院儿科,云南,昆明,650051
  • 2. 昆明医学院第一附属医院儿科,云南,昆明,650032
  • 折叠

摘要

Abstract

Objective To analyze understand whether norovirus infections, or norovirus and rotavirus infection in infants and young children with diarrhea in autumn and winter (from September to December) in 2007 and 2008 in Kunming, and analyze the clinical characteristics of infection. Methods We collected 96 stool specimens of children with diarrhea (including 46 specimes in 2007 and 50 in 2008) hospitalized in the department of Pediatrics, The lrst Affiliated Yanan Hospital of Kunming Medical University from September to December in 2007 and 2008. Colloidal Gold method was used to detect the antigen of group A rotavirus, and reverse transcription-polymerase chain reaction (RT-PCR) was used to detect the DNA of norovirus. Results RV infection was found in 60 children of all 96 children with diarrhea, the positive detection rate was 62.5%, and NoV infection was found in 12 children, and the positive detection rate was 12.5%. Both viruses infection was found in 5 children, and the positive detection rate was 5.2%. Conclusions Rotavirus is the most common pathogen of diarrhea in children in autumn and winter in Kunming, followed by norovirus, mixed infection of two viruses also can be found in some children. Mixed infection may aggravate the clinical symptoms, extend the course of disease, and increase the incidence of complications.

关键词

诺如病毒/轮状病毒/病毒性肠炎

Key words

Norovirus/ Rotavirus/ Viral enteritis

分类

临床医学

引用本文复制引用

李克蓉,曹虹,周锦妍,汪艳,杨娟,黄永坤..腹泻患儿诺如病毒和轮状病毒感染96例临床特点分析[J].昆明医学院学报,2011,32(1):86-89,4.

昆明医学院学报

OACSTPCD

1003-4706

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