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甘薯提取物体外促进PC12和SK-N-SH细胞增殖及突起生长作用研究

孙丽华 郑晓亮 颜冬梅 屠凌岚 李昉赟 王茵

天然产物研究与开发2011,Vol.23Issue(1):149-152,4.
天然产物研究与开发2011,Vol.23Issue(1):149-152,4.

甘薯提取物体外促进PC12和SK-N-SH细胞增殖及突起生长作用研究

Effects of Sweet Potato Extract on Promoting PC12 and SK-NSH Cells Proliferation and Neurite Outgrowth in Vitro

孙丽华 1郑晓亮 1颜冬梅 1屠凌岚 1李昉赟 1王茵1

作者信息

  • 1. 浙江省医学科学院,杭州,310013
  • 折叠

摘要

Abstract

An investigation was made on observe the effect of sweet potato extract on promoting PC12 and SK-N-SH cells proliferation and neurite outgrowth.Using PC12 and SK-N-SH cells cultured in vitro,as detecting the living rates of PC12 and SK-N-SH cells by MTT and calculating positive cell rate of which length of neurite exceeding 2 times of the neural body or the number of neurite exceeding 3, to evaluate the promoting effect of sweet potato on PC12 and SK-N-SH cells proliferation and neurite outgrowth.The results showed that sweet potato extract is able to promote PC12 and SK-N-SH cells neurite outgrowth and to increase the number of positive cells, has a certain neurotrophic effect and it is a good neuroprotective agent.

关键词

甘薯提取物/PC12细胞/SK-N-SH细胞/增殖/突起生长

Key words

sweet potato extract/ PC 12 cells/ SK-N-SH cells/ proliferation/ neurite outgrowth

分类

医药卫生

引用本文复制引用

孙丽华,郑晓亮,颜冬梅,屠凌岚,李昉赟,王茵..甘薯提取物体外促进PC12和SK-N-SH细胞增殖及突起生长作用研究[J].天然产物研究与开发,2011,23(1):149-152,4.

基金项目

浙江省科技厅重大专项项目(2007C12074) (2007C12074)

天然产物研究与开发

OA北大核心CSCDCSTPCD

1001-6880

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