摘要
Abstract
Objective To investigate the clinical effects of the treatment of non-invasive positive pressure ventilation for AECOPD with type II respiratory failure.Methods 144 cases of hospitalized patients were randomly divided into two groups.who were treatted in the Department of Respiratory Medicine and ICU from January 2008 to August 2009,observation group (NIPPV) with 72 cases and the control group (non-NIPPV) with 72 cases.In the control group,they were dealled with routine treatment, including anti-infection,spasmolysis and anti-asthma,expectorant,correcting water-electrolyte disorders and acid-base balance disorders, bronchodilators, airway smooth.eontinuous flow of oxygen at the end, with respiratory stimulants and nutritional support,treatment.In the observation group,on the basic of conventional treatment,the treatment of non-invasive breathing machine.Compare the blood gas analysis index changes (respiratory rate RR, heart rate, HR, pH value, PaO2, PaCO2, hospitalization duration, the trachea intubation rate and mortality indicators of these two groups.Results In the observation group.compared to the situation before the treatment.the indicators of blood gas analysis has significantly improved,the hospitalization was shorter.intubation rate was 15.28%, mortality was 8.33%;In the control group,the rate of traeheal intubation was 47.22%,and mortality was 34.72%,there was significant difference between these two groups(P<0.05).Conclusions NIPPV treatment for the AECOPD with type II respiratory failure is an effective way to alleviate the patient's respiratory muscle fatigue.to improve oxygenation,and can effectively reduce the PaC02,respiratory rate and mortality,and it also can avoid endotracheal intubation.关键词
慢性阻塞性肺疾病/急性加重期/Ⅱ型呼吸衰竭/无创正压通气Key words
Acute exacerbation chronic obstructive pulmonary disease/II -type respiratory failure/Non-invasive positive pressure ventilation
