现代检验医学杂志2011，Vol.26Issue(1)：56-58,3.DOI:10.3969/j.issn.1671-7414.2011.01.021
酶联免疫吸附试验检测促甲状腺激素受体抗体初探
Study the Significance of Detect TRAb with ELISA
摘要
Abstract
Objective To study the significance of detect TRAb with ELISA. Methods Detected serum concentration of TRAb of the Graves patients with RRA and ELISA in the same time,and compare the correlation of RRA and ELISA. Then detected the serum concentration of TRAb of 52 Graves patients at different clinical stage. At the same time,detect FT3,FT4 and TSH with chemiluminescence. Results Linear correlation analysis of RRA and ELISA with NCCLS EP9 A,showed good correlation (r = 0. 913 7). Matched t test of RRA and ELISA,there was no significant difference (P＞ 0. 05). The positive rate of TRAb of the group without treatment was higher than the group with treatment(P＜0.01). The recurrence rate of TRAb positive patients after the patients stopped the medicine was higher than patients of TRAb negative. Conclusion ELISA could be used in stead of RRA to detect TRAb. TRAb is important to the treatment and predication of recurrence of Graves disease ,but it is not fit to judge the thyroid function.关键词
酶联免疫吸附试验/促甲状腺激素受体抗体/毒性弥漫性甲状腺肿又称Graves[(GD)]分类
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邢晓光..酶联免疫吸附试验检测促甲状腺激素受体抗体初探[J].现代检验医学杂志,2011,26(1):56-58,3.
