首页|期刊导航|中国海洋湖沼学报（英文版）|Proteomic aspects of infection by lymphocystis disease virus in Japanese flounder (Paralichthys olivaceus)
中国海洋湖沼学报（英文版）2011，Vol.29Issue(3)：603-608,6.DOI:10.1007/s00343-011-0060-4
Proteomic aspects of infection by lymphocystis disease virus in Japanese flounder (Paralichthys olivaceus)
Proteomic aspects of infection by lymphocystis disease virus in Japanese flounder (Paralichthys olivaceus)
摘要
Abstract
To reveal the key factor in self-healing from LCDV (lymphocystis disease virus)-infected Japanese flounder (Paralichthys olivaceus), serum proteins from self-healing and sick Japanese flounder were separated by two-dimensional electrophoresis to screen differentially expressed proteins. Protein spots demonstrating changes greater than two-fold in the expression level were digested and further identified in capillary liquid chromatography tandem mass spectrometry (LC-MS/MS). Two immunity relevant proteins were thus identified as transferrin and the complement component C3 of Japanese flounder. These findings suggest that the two proteins may play important roles in the self-healing of lymphocystis in Japanese flounder. This is an important theoretical foundation to promote self-healing in LCDV-infected Japanese flounder by improving their innate immunity.关键词
Japanese flounder/Paralichthys olivaceus/lymphocystis disease/proteomics/serumKey words
Japanese flounder/Paralichthys olivaceus/lymphocystis disease/proteomics/serum引用本文复制引用
XING Mingqing,SUN Xiuqin,ZHENG Fengrong,QU Lingyun,HONG Xuguang,WU Suqi,ZHENG Minggang,ZHANG Jinxing..Proteomic aspects of infection by lymphocystis disease virus in Japanese flounder (Paralichthys olivaceus)[J].中国海洋湖沼学报（英文版）,2011,29(3):603-608,6.基金项目
Supported by the National High Technology Research and Development Program of China(863 program)(No.2006AA100309) （863 program）
