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HPLC法测定口腔溃疡膜中氢化可的松的含量

哈娜 哈力 杨习江

中国药房2011,Vol.22Issue(20):1908-1910,3.
中国药房2011,Vol.22Issue(20):1908-1910,3.

HPLC法测定口腔溃疡膜中氢化可的松的含量

Content Determination of Hydrocortisone in the Film of Oral Ulcer

哈娜 1哈力 1杨习江1

作者信息

  • 1. 哈尔滨医科大学第一临床医学院药学部,哈尔滨市150001
  • 折叠

摘要

Abstract

OBJECTIVE: To establish the method for the content determination of hydrocortisone in the tim of oral ulcer.METHODS: HPLC method was adopted. The column was Sinochrom ODS-BP column with mobile phase consisted of acetonitrile-water (50:50) at flow rate of 1.0 mL·min-1. The detection wavelength was set at 245 nm and the injection volume was 10 μL.RESULTS: The linear range of hydrocortisone was 0.209 2~1.559 0 μg(r=0.999 9); The average recoveries were 102.8% (RSD=1.59%), 102.4% (RSD=1.35%), 102.9% (RSD=0.77%), respectively. CONCLUSION: The method is simple, rapid,well-separated and accurate for the content determination of hydrocortisone in oral ulcer film.

关键词

高效液相色谱法/口腔溃疡膜/氢化可的松/含量测定

Key words

HPLC/ Oral ulcer film/ Hydrocortisone/ Content determination

分类

医药卫生

引用本文复制引用

哈娜,哈力,杨习江..HPLC法测定口腔溃疡膜中氢化可的松的含量[J].中国药房,2011,22(20):1908-1910,3.

中国药房

OACSCDCSTPCD

1001-0408

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