中国畜牧兽医2011,Vol.38Issue(5):48-54,7.
玉米赤霉烯酮对小鼠脾淋巴细胞增殖及分泌细胞因子的影响
Effects of ZEN on in vitro Proliferation and Cytokines Production of Spleen Lymphocyte in Mice
摘要
Abstract
The effects of ZEN on lymphocyte proliferation and cytokines production in vitro by MTT methods and cytokine ELISA methods were analyzed.The results showed that,in concentrations from 1 to 25 μg/mL, ZEN possess extremely significant inhibitory action to LPS or ConA-activated spleen lymphocytes proliferation (P<0.01)and this kind of inhibitory action was found to be dose-dependent.Higher doses ZEN(10, 25 μg/mL) possess extremely significantly inhibitory action to spleen iymphocytes in IL-10 and IFN-γ production (P<0.01), and showed dose-dependent.关键词
玉米赤霉烯酮/细胞因子/细胞增殖/脾脏淋巴细胞/小鼠Key words
Zearalenone/cytokines/proliferation/ spleen lymphocytes/mice分类
农业科技引用本文复制引用
范小龙,刘长永,剡海阔,邓衔柏,王磊,梁梓森,马勇江..玉米赤霉烯酮对小鼠脾淋巴细胞增殖及分泌细胞因子的影响[J].中国畜牧兽医,2011,38(5):48-54,7.基金项目
广东省自然科学基金项目(06300429). (06300429)