中国畜牧兽医2011，Vol.38Issue(5)：74-77,4.
转基因小鼠中应用RNAi的初步探讨
Application of RNAi in Trangenic Mice
摘要
Abstract
RNA interference degrades mRNA specifically and potently though the mediation of corresponding double-stranded RNA and leads to post-transcriptional gene silencing. Recently,small interfering RNA duplexes(siRNA) is used in mammalian cells to silence gene expression. At the same time,RNAi is a powerful tool for studying gene function in vivo. This review provides an overview of transgenic RNA interference in mice.关键词
RNA干扰/RNA双链/转基因小鼠Key words
RNA interference/ double-stranded RNA/ transgenic mice分类
生物科学引用本文复制引用
陈志宝,王东旭,万家余,潘朋朋,李莎,高宏伟..转基因小鼠中应用RNAi的初步探讨[J].中国畜牧兽医,2011,38(5):74-77,4.基金项目
国家自然科学基金资助项目(30972197 （）
31072148). （）
