癌变·畸变·突变2011,Vol.23Issue(3):209-212,4.DOI:10.3969/j.issn.1004-616x.2011.03.012
一次性筷子、牙签及纸杯浸提液对小鼠L-929细胞的毒性作用
Toxic effects of the extracted solution of disposable chopstick toothpick or cup in murine L-929 cells
摘要
Abstract
OBJECTIVE: To evaluate the toxic effects of the extracted solution of disposable chopstick, toothpick or cup in murine L-929 cells. METHODS: According to the national standards, we prepared cell culture medium with the extracted solution of disposable chopsticks, toothpicks or cups. The cell morphology of murine L-929 cells was examined microscopically and cell viability was detected with WST-1 staining method. The detached cell ratios and the relative growth rate of L-929 cells were calculated. RESULTS: Compared with the control, after treatment for 4 days or 7 days, cells in the experimental groups showed signs of apoptosis or necrosis. The detached cell ratios were increased significantly(P<0.05), while cell viability and relative growth rate declined significantly(P<0.05).CONCLUSION: Treatments with extracted solution of disposable chopstick, toothpick or cup could affect cell growth and proliferation, thus probably possess potential toxic effects.关键词
牙签/一次性筷子/一次性纸杯/细胞毒性Key words
toothpick/ disposable chopstick/ disposable cup/ cytotoxicity分类
医药卫生引用本文复制引用
陈思凡,李文学,贾慧影,陈建玲,杨光宇,朱伟..一次性筷子、牙签及纸杯浸提液对小鼠L-929细胞的毒性作用[J].癌变·畸变·突变,2011,23(3):209-212,4.基金项目
广州市科技计划项目(2009Z1-E061) (2009Z1-E061)