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一次性筷子、牙签及纸杯浸提液对小鼠L-929细胞的毒性作用

陈思凡 李文学 贾慧影 陈建玲 杨光宇 朱伟

癌变·畸变·突变2011,Vol.23Issue(3):209-212,4.
癌变·畸变·突变2011,Vol.23Issue(3):209-212,4.DOI:10.3969/j.issn.1004-616x.2011.03.012

一次性筷子、牙签及纸杯浸提液对小鼠L-929细胞的毒性作用

Toxic effects of the extracted solution of disposable chopstick toothpick or cup in murine L-929 cells

陈思凡 1李文学 2贾慧影 1陈建玲 2杨光宇 1朱伟2

作者信息

  • 1. 广州市疾病预防控制中心,广东广州510080
  • 2. 中山大学公共卫生学院,广东广州510080
  • 折叠

摘要

Abstract

OBJECTIVE: To evaluate the toxic effects of the extracted solution of disposable chopstick, toothpick or cup in murine L-929 cells. METHODS: According to the national standards, we prepared cell culture medium with the extracted solution of disposable chopsticks, toothpicks or cups. The cell morphology of murine L-929 cells was examined microscopically and cell viability was detected with WST-1 staining method. The detached cell ratios and the relative growth rate of L-929 cells were calculated. RESULTS: Compared with the control, after treatment for 4 days or 7 days, cells in the experimental groups showed signs of apoptosis or necrosis. The detached cell ratios were increased significantly(P<0.05), while cell viability and relative growth rate declined significantly(P<0.05).CONCLUSION: Treatments with extracted solution of disposable chopstick, toothpick or cup could affect cell growth and proliferation, thus probably possess potential toxic effects.

关键词

牙签/一次性筷子/一次性纸杯/细胞毒性

Key words

toothpick/ disposable chopstick/ disposable cup/ cytotoxicity

分类

医药卫生

引用本文复制引用

陈思凡,李文学,贾慧影,陈建玲,杨光宇,朱伟..一次性筷子、牙签及纸杯浸提液对小鼠L-929细胞的毒性作用[J].癌变·畸变·突变,2011,23(3):209-212,4.

基金项目

广州市科技计划项目(2009Z1-E061) (2009Z1-E061)

癌变·畸变·突变

OACSCDCSTPCD

1004-616X

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