浙江医学2011，Vol.33Issue(7)：1046-1047,1097,3.
Ezrin蛋白在子宫内膜异位症中的表达及意义
Expression of ezrin in endometriosis and its clinicopathological significance
丁海钢 1华凯 1包磊2
作者信息
- 1. 312000,绍兴市妇幼保健院妇科
- 2. 312000,绍兴市妇幼保健院病理科
- 折叠
摘要
Abstract
Objective To investigate the expression of ezrin in endometriosis and its clinicopathological significance.Methods Ninety specimens from patients with endometriosis, including 60 specimens of ovarian endometriosis and 30 specimens of eutopic endometrium were collected; and 20 specimens of normal endometrium served as a controls.The expression of ezrin in ectopic and eutopic endometrium of endometriosis and in normal endometrium was detected by immunohistochemistry Envision TM method.Results Immunohistochemistry showed that the expression of ezrin in eutopic from women with endometriosis was higher than that in normal endometrium.The expression of ezrin in ectopic was higher than that in eutopic endometrium of endometriosis.The levels of ezrin expression in ectopic and eutopic endometrium from woman with severe endometriosis were much higher than those with mild endometriosis (all P＜0.05).Conclusion The expression levels of ezrin were significantly correlated with the clinical stage of endometriosis, which suggests that ezrin might play an important role in development of endometriosis.关键词
Ezrin/子宫内膜异位症/在位内膜/异位内膜Key words
Ezrin / Endometriosis / Eutopic endometrium / Ectopic endometrium引用本文复制引用
丁海钢,华凯,包磊..Ezrin蛋白在子宫内膜异位症中的表达及意义[J].浙江医学,2011,33(7):1046-1047,1097,3.
