浙江医学2011，Vol.33Issue(7)：993-996,4.
左旋布比卡因复合芬太尼腰硬联合麻醉在剖宫产手术中的效用
Spinal and epidural anesthesia using varied doses of levobupivacaine combined with fentanyl in cesarean section
陈悦 1严美娟 1楼小侃 1于泳健1
作者信息
- 1. 310014,杭州,浙江省人民医院麻醉科
- 折叠
摘要
Abstract
Objective To evaluate the application of spinal and epidural anesthesia using varied doses of isobaric levobupivacaine combined with fentanyl for caesarean section.Methods Sixty ASA I nulliparous women with a singleton full- term pregnancy scheduled for caesarean section under combined spinal and epidural anesthesia (CESA) were randomly allocated to one of 3 groups (n=20 each):group A received isobaric levobupivacaine 7.5mg, group B 10 mg and group C 12.5mg.All groups also received fentanyl 20μg and diluted with cerebrospinal fluid to 3ml.The upper level of sensory block and the Bromage score of maximum motor block were recorded.Time ofsensory and motor block, time to peak sensory and maximum motor block, duration of analgesia and motor block and quality of spinal anesthesia during operation were recorded.Hemodynamics,side effects and fetal outcome were also recorded.Results The upper level of sensory block in group C was significantly higher than that in group A and B, and that in group B higher was than in group A (P＜0.05).Time to peak level of sensory block and maximum motor block in group C was significantly shorter than that in group A(P＜0.05).Duration of analgesia and motor block in group C was significantly longer than that in group A (P＜0.05).There was no significant difference in onset time of motor block,Bromage score of maximum motor block, feeling of pain during operation among three groups.The incidence of hypotension and bradyarrhythmia in group C was higher than that of in group A and more patients in group C were received ephedrine.There was higher incidence of nausea and vomiting in group C than that in group A and B.There was no significant difference in the incidence of headache, itch and Apgar scores of the newborn among the three groups.Conclusion 7.5mg levobupivacaine combined with fentany 120μg in CSEA can produce satisfactory sensory and motor block for caesarean section, and can increase the stability of hemodynamics.关键词
左旋布比卡因/芬太尼/麻醉/脊髓/剖宫产Key words
Levobupinacaine /Fentanyl /Anesthesia /Spinal /Caesarean section引用本文复制引用
陈悦,严美娟,楼小侃,于泳健..左旋布比卡因复合芬太尼腰硬联合麻醉在剖宫产手术中的效用[J].浙江医学,2011,33(7):993-996,4.
