浙江医学2011，Vol.33Issue(7)：1032-1033,1036,3.
血尿酸水平与冠状动脉病变严重程度的相关性分析
Relationship between serum uric acid levels and the severity of coronary lesions in patients with coronary heart disease
王品晓 1杨鹏麟 2林加峰 2季亢挺 2李嘉2
作者信息
- 1. 温州医学院
- 2. 325000,温州医学院附属第二医院心内科
- 折叠
摘要
Abstract
Objective To investigate the relationship between the serum uric acid levels and the severity of coronary lesions in patients with coronary heart disease.Methods Three hundred and thirty eight patients who underwent coronary angiography were classified as single- vessel disease group (n 100), double- vessel disease groups (n=76) and triple- vessel disease groups (n= 160) according to the number of vessels with significant stenosis The serum uric acid levels and other clinical biochemical parameters were detected, and the relationship between the serum uric acid level and coronary lesions were analyzed.Results The serum uric acid levels of single- vessel disease group, double- vessel disease group and triple- vessel disease group were (291.66± 50.23) , (368.97± 74.49)and (415.01± 82.27) μ mol/L, respectively (P＜0.01).Bivariate Correlations analysis revealed that serum uric acid was significantly associated with coronary lesions (P＜0.01).The total cholesterol(TC), low density lipoprotein cholesterol(LDL- C), hypertension and sex were also significantly associated with coronary lesions (P＜0.01)and age,smoking, diabetes were relevant with coronary lesions (P＜0.05).But triglycerides (TG), high density lipoprotein cholesterol (HDL- C)were not associated with coronary lesions (P＞0.05).The further Partial Correlations analysis showed that serum uric acid was significantly associated with coronary lesions after other risk factors were adjusted.Linear Regression analysis revealed the linear regression equation as y=0.104+0.006x.Conclusion Serum uric acid levels are correlated with atherosclerotic heart disease and the severity of coronary lesions, which indicates that the measurement of serum uric acid may be of value in predicting coronary heart disease events.关键词
冠状动脉病变/尿酸/冠状动脉造影Key words
Coronarylesions/ Uric acid/ Coronary angiography引用本文复制引用
王品晓,杨鹏麟,林加峰,季亢挺,李嘉..血尿酸水平与冠状动脉病变严重程度的相关性分析[J].浙江医学,2011,33(7):1032-1033,1036,3.
