浙江医学2011，Vol.33Issue(7)：1034-1036,3.
甲状腺激素对糖化白蛋白作用的研究
Correlation of serum glycated albumin with thyroid hormone levels
孙玲 1袁兆林 2张晓雪 2沈波 2吕时铭3
作者信息
- 1. 317000,浙江省台州医院妇产科
- 2. 317000,浙江省台州医院检验科
- 3. 浙江大学医学院附属妇产科医院检验科
- 折叠
摘要
Abstract
Objective To investigate the correlation of serum glycated albumin (GA) with thyroid hormone levels.Methods Seven patients with untreated hypothyroidism and 32 patients with untreated thyrotoxicosis were enrolled in the study, and 17 healthy, non-diabetic, euthyroid individuals served as controls.Serum GA, 2-h postprandial blood glucose were measured by enzymatic method; thyroid- stimulating hormone (TSH), free triiodothyronine (T3) and free thyroxine (T4) were measured by chemiluminescent immunoassay (CLIA).Results Serum GA levels were significantly higher in patients with hypothyroidism[(14.6± 3.01)％, P＜0.01]and lower in patients with thyrotoxicosis [(10.4± 1.82)％, P＜0.01]compared to controls [(12.0± 1.13)％].Serum GAlevels were positively correlated with serum TSH levels (r=0.39, P＜0.01) and negatively correlated with serum free T3(r=- 0.512, P＜0.01) and serum free T4 (r=- 0.619, P＜0.01) levels.Conclusion Serum GA levels are correlated with thyroid hormone, which indicates that thyrotoxicosis or other thyroid hormone- related conditions should be considered when serum GA is abnormal.关键词
甲状腺功能亢进/甲状腺功能减退/糖化白蛋白Key words
Hyperthyroidism / Hypothyroidism / GA引用本文复制引用
孙玲,袁兆林,张晓雪,沈波,吕时铭..甲状腺激素对糖化白蛋白作用的研究[J].浙江医学,2011,33(7):1034-1036,3.
