西南国防医药2011，Vol.21Issue(8)：832-834,3.DOI:10.3969/j.issn.1004-0188.2011.08.006
光纤药物溶出度实时测定仪监测氨茶碱片溶出度
Real-time assay of aminophylline dissolution by fiber optic dissolution test system
钟元高 1张涛 1廖昌军 2王艳丽 1何德云1
作者信息
- 1. 610017,成都,成都军区联勤部药品仪器检验所
- 2. 成都医学院药学院
- 折叠
摘要
Abstract
Objective To make comparison of advantages and disadvantages between fiber optic method and pharmacopia -recommended method for the assay of aminophylline tablets dissolution. Methods A fiber optic dissolution test system, FODT - 601, was used to determine eight batches of aminophlline made in a domestic factory. The results were compared with those obtained by pharmacopia - recommended method. Results In general, dissolution rates of aminophylline samples assayed by fiber optic method were higher than those by pharmacopia - recommended method. There were great differences in real - time dissolution curve among eight batches of aminophylline. Conclusion Fiber optic dissolution test system can fulfil real - time assay of aminophylline dissolution. Moreover, it can objectively reflect the whole dissolving process of aminophylline.关键词
光纤药物溶出度实时测定仪/氨茶碱片/溶出度Key words
fiber optic dissolution test system/ aminophylline tablet/ dissolution分类
医药卫生引用本文复制引用
钟元高,张涛,廖昌军,王艳丽,何德云..光纤药物溶出度实时测定仪监测氨茶碱片溶出度[J].西南国防医药,2011,21(8):832-834,3.
