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早期糖尿病肾病患者血糖漂移度与尿蛋白排泄率相关性分析

贺海东 陈桢 徐旭东

江苏大学学报(医学版)2011,Vol.21Issue(4):357-359,3.
江苏大学学报(医学版)2011,Vol.21Issue(4):357-359,3.

早期糖尿病肾病患者血糖漂移度与尿蛋白排泄率相关性分析

Correlation between amplitude of blood glucose excursions and urinary albumin excretion rate in patients with early stage of diabetic nephropathy

贺海东 1陈桢 2徐旭东1

作者信息

  • 1. 上海市闵行区中心医院肾内科,上海,201199
  • 2. 上海市徐汇区中心医院肾内科,上海,200030
  • 折叠

摘要

Abstract

Objective: To analysis the relationship between amplitude of blood glucose excursions and urinary album in excretion rate in patients with early stage of diabetic nephropathy. Methods: One hundred and twenty-eight patients with early stage of diabetic nephropathy were recruited. All the patients were submitted to continuous glucose monitoring system( CGMS) . According to the result of CGMS monitoring, the patients were divided into two groups: high glucose excursion group( 60 cases) and low glucose excursion group (68 cases) . To test urinary protein excretion rate ( UAER) by collecturine specimens. Results: ①UAER of high blood glucose excursion group was( 85. 5 ±30. 7) μg/ min, and low glucose excursion group was ( 67. 5 ±24. 5) μg/ m in with significant difference( P < 0. 05) . ② Stepwise regression analysis showed that the standard deviation of blood glucose was involved in regression mode( r= 0. 206 , P < 0. 05 ) . Conclusion : In early stage of diabetic nephropathy patients, blood glucose excursions was related with UAER,which suggested that the blood glucose excursionsmay be the risk factor to UAER.

关键词

糖尿病肾病/血糖漂移/尿蛋白排泄率

Key words

diabetic nephropathy/ blood glucose excursions/ urinary album in excretion rate

分类

医药卫生

引用本文复制引用

贺海东,陈桢,徐旭东..早期糖尿病肾病患者血糖漂移度与尿蛋白排泄率相关性分析[J].江苏大学学报(医学版),2011,21(4):357-359,3.

江苏大学学报(医学版)

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