中国卒中杂志2011，Vol.6Issue(5)：366-370,5.
单侧颈动脉闭塞脑梗死和侧支代偿情况分析
Analysis of Cerebral Infarction and Collateral Flow in Patients with Unilateral Carotid Artery Occlusion
李尧 1何晋涛 1吴继星 1侯晶晶 1唐华 1白维 1刘阳 1张娟1
作者信息
- 1. 100007,北京市,北京市第六医院神经内科
- 折叠
摘要
Abstract
Objective To investigate the cerebral infarction by computer tomography (CT) and magnetic resonance imaging (MRI) ipsilateral to carotid artery occlusion in patients with unilateral carotid artery occlusion and the association between ischemic brain lesions and intracranial collateral blood flow. To promote our understanding of the pathophysiology of cerebral ischemia.Methods Forty-three patients with unilateral carotid artery occlusion confirmed by coratid ultrasound were included. The numbers of infarction were compared in each of five cerebral anatomic regions ipsilateral to the occlusion. The five regions were territory cortical region of middle cerebral artery (MC), anterior watershed cortical region (AWS), posterior watershed cortical region (PWS), internal watershed region (IWS), and perforating artery region (PA). The associations between collateral blood flow pattern and infarction in five regions were analyzed.Results The frequency of lWS infarcts in the hemisphere ipsilateral to the occluded carotid artery was higher (n=17, 44.2％). Six of eight AWS infarcts coexisted with IWS infarcts. The presence of Posterior communicating artery (PCoA) was a protective factor associated with a reduction in prevalence of IWS infarcts (odd ratio (OR) =0.226, 95％ confidence interval (CI）: 0.058-0.833,P=0.027).Conclusion Higher frequency of IWS infarcts and most of AWS infarcts coexisted with IWS infarcts suggested a hemodynamic mechanism for stroke with occlusive coratid disease. PCoA was a protective factor associated with a reduction in prevalence of IWS infarcts.关键词
颈动脉闭塞/血液动力学/脑缺血Key words
Carotid stenosis: Hemodynamics/ Brain ischemia引用本文复制引用
李尧,何晋涛,吴继星,侯晶晶,唐华,白维,刘阳,张娟..单侧颈动脉闭塞脑梗死和侧支代偿情况分析[J].中国卒中杂志,2011,6(5):366-370,5.
