重庆医学2011，Vol.40Issue(20)：1995-1996,2.DOI:10.3969/j.issn.1671-8348.2011.20.007
78例食管癌患者CK20mRNA、CD44v6、NF-κB表达的临床意义
Expressions of CK20 mRNA,CD44v6, NF-κB in the 78 cases of esophageal carcinoma
李斌 1李劲松 1袁宁1
作者信息
- 1. 重庆市第三人民医院体检中心,400014
- 折叠
摘要
Abstract
Objective To detect the expressions of CK20 mRNA,CD44v6,NF κB in the blood or tissues of 78 cases esophageal carcinoma and the clinical meanings. Methods The expressions of CK20 mRNA in blood and CD44v6,NF-κB in tissue in 78 cases esophageal carcinoma were examined with immunohistochemical technique. Results Positive rats of the expression of CK20 mRNA in blood with esophageal carcinoma was 72 ％, and 30.7 ％, 55 ％, 92 ％, 100 ％ respectively in TNM Ⅰ , Ⅱ , Ⅲ, Ⅳ. Positive of the expression of CD44v6 in the tissue of esophageal carcinoma was 59 ％, while the rate of the NF κB expression was 76.9 ％. There was significant difference between the expression of NF κB and the lymphatic metastasis. Conclusion The expression of the CK20 mRNA and CD44v6 in esophageal carcinoma is correlated with blood metastasis, and the expression of the NF κB is correlated with lymphatic metastasis.关键词
食管肿瘤/免疫组织化学/核因子-κB/CD44v6/CK20Key words
esophageal neoplasms/ immunohistochemistry/ NF kappa B/ CD44v6/ CK20引用本文复制引用
李斌,李劲松,袁宁..78例食管癌患者CK20mRNA、CD44v6、NF-κB表达的临床意义[J].重庆医学,2011,40(20):1995-1996,2.
