中国实用外科杂志2011,Vol.31Issue(5):398-401,4.
甲状腺髓样癌诊治的若干问题
Discussion in the diagnosis and treatment of medullary thyroid cancer
陈曦1
作者信息
- 1. 上海交通大学医学院附属瑞金医院外科,上海,200025
- 折叠
摘要
Abstract
Medullary thyroid cancer (MTC) originates from parafollicular C cells of the thyroid gland, and accounts for about 4% of thyroid cancer cases. MTC presents as part of an autosomal dominant inherited disorder related to multiple endocrine tumor type 2 (MEN-2) in about 20% ~ 25% of cases, including MEN-2a, MEN-2b and family MTC, and as a sporadic tumor in the remainder. Calcitonin is a specific tumor marker of MTC, which indicates the tumor onset, residue and recurrence. Calcitonin doubling-time is related to the prognosis. The only possible to cure MTC is total thyroidectomy and lymph node dissection, and the prophylactic surgery benefits the MEN-2 related patients.关键词
甲状腺髓样癌/降钙素/全甲状腺切除术/基因测序Key words
medullary thyroid carcinoma/ calcitonin/ total thyroidectomy/ gene sequencing分类
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陈曦..甲状腺髓样癌诊治的若干问题[J].中国实用外科杂志,2011,31(5):398-401,4.