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甲状腺髓样癌诊治的若干问题

陈曦

中国实用外科杂志2011,Vol.31Issue(5):398-401,4.
中国实用外科杂志2011,Vol.31Issue(5):398-401,4.

甲状腺髓样癌诊治的若干问题

Discussion in the diagnosis and treatment of medullary thyroid cancer

陈曦1

作者信息

  • 1. 上海交通大学医学院附属瑞金医院外科,上海,200025
  • 折叠

摘要

Abstract

Medullary thyroid cancer (MTC) originates from parafollicular C cells of the thyroid gland, and accounts for about 4% of thyroid cancer cases. MTC presents as part of an autosomal dominant inherited disorder related to multiple endocrine tumor type 2 (MEN-2) in about 20% ~ 25% of cases, including MEN-2a, MEN-2b and family MTC, and as a sporadic tumor in the remainder. Calcitonin is a specific tumor marker of MTC, which indicates the tumor onset, residue and recurrence. Calcitonin doubling-time is related to the prognosis. The only possible to cure MTC is total thyroidectomy and lymph node dissection, and the prophylactic surgery benefits the MEN-2 related patients.

关键词

甲状腺髓样癌/降钙素/全甲状腺切除术/基因测序

Key words

medullary thyroid carcinoma/ calcitonin/ total thyroidectomy/ gene sequencing

分类

医药卫生

引用本文复制引用

陈曦..甲状腺髓样癌诊治的若干问题[J].中国实用外科杂志,2011,31(5):398-401,4.

中国实用外科杂志

OA北大核心CSCDCSTPCD

1005-2208

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