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血管性痴呆的药物治疗研究进展

骆迪 毕齐

中国卒中杂志2011,Vol.6Issue(5):423-426,4.
中国卒中杂志2011,Vol.6Issue(5):423-426,4.

血管性痴呆的药物治疗研究进展

Research of Drug Treatment of Vascular Dementia

骆迪 1毕齐1

作者信息

  • 1. 100029,北京市,首都医科大学附属北京安贞医院神经内科
  • 折叠

摘要

Abstract

Vascular dementia is a kind of cognitive dysfunction clinical syndrome caused by cerebrovascular diseases. Relevant drug therapy includes anticholinesterase, N-aspatic acid methyl-D-receptor inhibitors, Nimodipine, statins and nicergoline etc. The efffect of donepezil is controversy; galanthamine is effective to the dementia caused by both Alzheimer disease (AD) and cerebrovascular diseases; rivastigmine in vascular dementia those who are old and may have AD has the obvious effect in cognitive; memantine in mild to moderate vascular dementia has good curative effect and tolerability; most tests show nimodipine in vascular cognitive dysfunction is an effective treatment, and have good safety; simastatin and atorvastatin are effective; nicergoline can inprove cognitive functions in vascular dementia patient. At present, there is no evidence that antiplatelet agents and antihypertensive drugs have positive treatment function.

关键词

痴呆,血管性/胆碱酯酶抑制剂/美金刚/尼莫地平/尼麦角林

Key words

Dementia, vascular/ Cholinesterase inhibitors/ Memantine/ Nimodipine/Nicergoline

引用本文复制引用

骆迪,毕齐..血管性痴呆的药物治疗研究进展[J].中国卒中杂志,2011,6(5):423-426,4.

中国卒中杂志

OACSTPCD

1673-5765

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