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Foxp3-6054基因多态性与变应性结膜炎的关系

杨瑞明 赖荷 沙翔垠 陈卫芳 陈盛强 樊飞红

广东医学2011,Vol.32Issue(14):1828-1830,3.
广东医学2011,Vol.32Issue(14):1828-1830,3.

Foxp3-6054基因多态性与变应性结膜炎的关系

Study on Foxp3-6054 polymorphisms in patients with allergic conjunctivitis

杨瑞明 1赖荷 2沙翔垠 1陈卫芳 1陈盛强 3樊飞红1

作者信息

  • 1. 广州医学院第二附属医院,眼科,广州,510260
  • 2. 广州医学院第二附属医院,过敏反应科,广州,510260
  • 3. 广州医学院第二附属医院,神经科学研究所,广州,510260
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摘要

Abstract

Objective To investigate the distribution of Foxp3 - 6054 ( deletion/ATT, rs5902434 ) gene in patients with allergic conjunctivitis and its correlation with the disease. Methods PCR - SSP was carried out in 63 unrelated patients with allergic conjunctivitis and 100 matched healthy control of Han nationality for genotyping of Foxp3 - 6054 ( deletion/ATT, rs5902434 ) gene. Results There was no significant difference in Foxp3 - 6054 ( deletion/ATT,rs5902434 ) genetyping between allergic conjunctivitis patients and controls ( P > 0. 05 ). Conclusion Foxp3 - 6054 ( deletion/ATT, rs5902434 ) is not associated with allergic conjunctivitis.

关键词

尘螨/变应性结膜炎/Foxp3-6054(deletion/ATT,rs5902434)/多态性

Key words

dust mites/ allergic conjunctivitis/ Foxp3 -6054 ( deletion/ATT, rs5902434 )/ polymorphisms

引用本文复制引用

杨瑞明,赖荷,沙翔垠,陈卫芳,陈盛强,樊飞红..Foxp3-6054基因多态性与变应性结膜炎的关系[J].广东医学,2011,32(14):1828-1830,3.

基金项目

省科技计划项目(编号:2010B031600139) (编号:2010B031600139)

广东医学

OA北大核心CSCDCSTPCD

1001-9448

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