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注射用头孢尼西钠与果糖注射液的配伍稳定性考察

惠慧 韩强

中国药房2011,Vol.22Issue(22):2061-2062,2.
中国药房2011,Vol.22Issue(22):2061-2062,2.

注射用头孢尼西钠与果糖注射液的配伍稳定性考察

Compatible Stability of Cefonicid Sodium for Injecfion with Fructose Injection

惠慧 1韩强1

作者信息

  • 1. 徐州医学院附属医院药剂科,徐州市,221002
  • 折叠

摘要

Abstract

OBJECTIVE: To investigate the compatible stability of Cefonicid sodium for injection with Fructose injection at room temperature (25 ± 1 ) ℃. METHODS: At room temperature (25 ± 1 ) ℃, Cefonicid sodium for injection 1.0 g was added into 10 mL Fructose injection. The appearance and pH value of mixture in 6 h were observed. The content of cefonicid was determined by HPLC, and whether new matter generated was investigated. RESULTS: At room temperature (25 ± 1 ) ℃, there were no changes in appearance, pH value and cefonicid sodium concentration of mixture within 0~6 h. CONCLUSION: At room temperature (25 ± 1 ) ℃, the compatibility of Cefonicid sodium for injection combined with Fructose injection is stable within 6h.

关键词

注射用头孢尼西钠/果糖注射液/配伍/稳定性/高效液相色谱法

Key words

Cefonicid sodium for injection/ Fructose injection/ Compatibility/ Stability/ HPLC

分类

医药卫生

引用本文复制引用

惠慧,韩强..注射用头孢尼西钠与果糖注射液的配伍稳定性考察[J].中国药房,2011,22(22):2061-2062,2.

中国药房

OACSCDCSTPCD

1001-0408

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