中国药房2011,Vol.22Issue(22):2061-2062,2.
注射用头孢尼西钠与果糖注射液的配伍稳定性考察
Compatible Stability of Cefonicid Sodium for Injecfion with Fructose Injection
惠慧 1韩强1
作者信息
- 1. 徐州医学院附属医院药剂科,徐州市,221002
- 折叠
摘要
Abstract
OBJECTIVE: To investigate the compatible stability of Cefonicid sodium for injection with Fructose injection at room temperature (25 ± 1 ) ℃. METHODS: At room temperature (25 ± 1 ) ℃, Cefonicid sodium for injection 1.0 g was added into 10 mL Fructose injection. The appearance and pH value of mixture in 6 h were observed. The content of cefonicid was determined by HPLC, and whether new matter generated was investigated. RESULTS: At room temperature (25 ± 1 ) ℃, there were no changes in appearance, pH value and cefonicid sodium concentration of mixture within 0~6 h. CONCLUSION: At room temperature (25 ± 1 ) ℃, the compatibility of Cefonicid sodium for injection combined with Fructose injection is stable within 6h.关键词
注射用头孢尼西钠/果糖注射液/配伍/稳定性/高效液相色谱法Key words
Cefonicid sodium for injection/ Fructose injection/ Compatibility/ Stability/ HPLC分类
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惠慧,韩强..注射用头孢尼西钠与果糖注射液的配伍稳定性考察[J].中国药房,2011,22(22):2061-2062,2.