中国药房2011，Vol.22Issue(23)：2135-2136,2.
23种中草药提取物对肺炎链球菌的抗菌作用研究
Antibacterial Effects of 23 Kinds of Chinese Herbal Medicine Extracts on Streptococcus Pneumoniae
余琼 1白志川 1孟德胜 2卢来春 2张雪梅 3傅若秋2
作者信息
- 1. 西南大学园艺园林学院,重庆市,400715
- 2. 第三军医大学第三附属医院,重庆市,400042
- 3. 重庆医科大学医学检验系,重庆市,400016
- 折叠
摘要
Abstract
OBJECTIVE: To evaluate the antibacterial activities of 23 kinds of Chinese herbal medicine extracts against Streptococcus pneumoniae (SPN) in vitro. METHODS: The minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) of 23 kinds of Chinese herbal medicine extract were determined by 96-well tissue culture microplates and smear method. The diameter of inhibition zone was compared using the Kirby-Baueer disc diffusion. RESULTS: 11 kinds of Chinese herbal medicines had antibacterial activities on SPN, such as Panax notoginseng, Chaenomeles speciosa, Scutellaria baicalensis. The ethanol extracts of P notoginseng and C. speciosa had the strongest antibacterial activities. The MIC, MBC of them were 1: 16,1: 8 and 1: 8, 1: 4. The diameter of inhibition zone was 15 mm. CONCLUSION: The ethanol extracts of P. notoginseng and C. speciosa have significant antibacterial effects.关键词
中草药/肺炎链球菌/最低抑菌浓度/最低杀菌浓度Key words
Chinese herbal medicines/ Streptococcus pneumoniae/ Minimal inhibitory concentration/ Minimal bactericidal concentration分类
医药卫生引用本文复制引用
余琼,白志川,孟德胜,卢来春,张雪梅,傅若秋..23种中草药提取物对肺炎链球菌的抗菌作用研究[J].中国药房,2011,22(23):2135-2136,2.
