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苯并异噻唑啉酮类衍生物的制备与生物活性测试

许凤玲 蔺存国 刘秀丽 徐伟

海洋科学2011,Vol.35Issue(4):67-69,76,4.
海洋科学2011,Vol.35Issue(4):67-69,76,4.

苯并异噻唑啉酮类衍生物的制备与生物活性测试

Synthesis and bioactivity of 3-carbonyl-benzo[d]isothiazol-3(2H)-methyl Benzoates Derivatives

许凤玲 1蔺存国 1刘秀丽 2徐伟3

作者信息

  • 1. 中船重工七二五所,海洋腐蚀与防护国防科技重点实验室,山东,青岛,266071
  • 2. 青岛中石油昆仑天然气利用有限公司,山东,青岛,266071
  • 3. 青岛保税港区管理委员会,山东,青岛,266071
  • 折叠

摘要

Abstract

Novel antifoulants were synthesized and their structures were confirmed by means of MS, elemental analysis, and 1H NMR. The antimicrobial activity of the compounds on five bacteria, including Escherichia coli,Staphyloccus aurueus, Vibrio alginolyticus, Aeromonas hydrophila, and Bacillus subtilis were tested. These compounds showed good antimicrobial activity, especially to Escherichia coli. When the compounds concentration were reached 10-6 g/L the viable cell were reduced by more than 90%. The novel synthesized compounds might be potential microbial inhibitors.

关键词

防污剂/苯并异噻唑酮/合成/生物活性

Key words

antifoulant/ benzisothiazolone/ synthesize/ bioactivity

分类

化学化工

引用本文复制引用

许凤玲,蔺存国,刘秀丽,徐伟..苯并异噻唑啉酮类衍生物的制备与生物活性测试[J].海洋科学,2011,35(4):67-69,76,4.

基金项目

国家自然科学基金项目(40376023) (40376023)

海洋科学

OA北大核心CSCDCSTPCD

1000-3096

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