中国药业2011，Vol.20Issue(15)：71-73,3.
替罗非班用于急性ST段抬高心肌梗死行急诊冠状动脉介入治疗25例
Emergent Percutaneous Coronary Intervention Combined with Tirofiban for Treating Acute ST - Segment Elevation Myocardial Infarction in 25 Cases
李屏 1郭忠玉 1李伟 1李安敏 1陈云1
作者信息
- 1. 贵阳医学院附属医院心内科,贵州,贵阳,550004
- 折叠
摘要
Abstract
Objective To investigate the clinical effect and safety of emergent percutaneous coronary intervention (PCI) combined with domestic tirofiban in treating acute ST- segment elevation myocardial infarction (STEMI). Methods Seventy-one consecutive patients with acute STEMI were divided into emergent PCI combined with tirofiban (tirofiban group, n =25) or emergent PCI treatment alone (control group, n =46). Left ventricular ejection fraction (LVEF) and major adverse cardiac events(MACE) during hospitalization period and at 30 d and 180 d after discharge were compared between the two groups. Results The immediate TIMI blood flow after the procedure,LVEF and the incidence of MACE during hospitalization period were significantly different between the tirofiban and control groups( P ＜0.05).LVEF and the incidence of MACE at 30 d follow up also showed significant difference(P＜ 0.05). LVEF at 180 d follow up was somewhat increased and the incidence of MACE at 180 d was somewhat reduced in tirofiban group without significant difference between the two groups(P ＞ 0.05). Conclusion Adjunctive therapy with tirofiban for the patients with acute STEMI undergoing emergent PCI is safe and effective.关键词
急性心肌梗死/经皮冠状动脉介入治疗/盐酸替罗非班/心肌梗死溶栓试验/主要不良心血管事件Key words
acute myocardial infarction/ percutaneous coronary intervention/ tirofiban hydrocloride/ TIMI/ MACE分类
医药卫生引用本文复制引用
李屏,郭忠玉,李伟,李安敏,陈云..替罗非班用于急性ST段抬高心肌梗死行急诊冠状动脉介入治疗25例[J].中国药业,2011,20(15):71-73,3.
