中国组织工程研究与临床康复2011，Vol.15Issue(20)：3653-3656,4.DOI:10.3969/j.issn.1673-8225.2011.20.011
兔下颌骨前牙区剩余牙槽嵴模型的建立
Establishment of a rabbit model of anterior residual alveolar ridge
摘要
Abstract
BACKGROUND: A proper anterior residual alveolar ridge model can provide basis for the preservation and repair of residual alveolar ridge.OBJECTIVE: to establish a rabbit animal model of anterior residual alveolar ridge.METHODS: The eighteen New Zealand white rabbits were selected, both side of central incisors of 18 rabbits were extracted under the general anesthesia to prepare anterior residual alveolar ridge models. Rabbits were killed at 4, 8, and 12 weeks after operation. The length, width and height of residual alveolar after extraction were measured by Vernier caliper. The healing process of teeth extraction was observed by hematoxylin-eosin staining. The remodeling of bone trabecula in after extraction was examined by X-ray.RESULTS AND CONCLUSION: The length, width and height of residual alveolar ridge were gradually decreased with time prolonged. Osteoblasts could be seen scattered in teeth extraction, new trabecular bone and vascular network was born. The deposition of new bone was continued in teeth extraction, the boundaries between new bone and the alveolar bone was not clear, and new bone and bone remodeling were happening in teeth extraction. Hemato关键词
剩余牙槽嵴/下颌骨前牙区/动物模型/兔/骨组织工程分类
医药卫生引用本文复制引用
胡杨,马莹,何惠宇..兔下颌骨前牙区剩余牙槽嵴模型的建立[J].中国组织工程研究与临床康复,2011,15(20):3653-3656,4.基金项目
新疆维吾尔自治区科技厅科技攻关项目(200533118),课题名称:组织工程骨用于即刻牙种植的骨结合研究 （200533118）
新疆维吾尔自治区高校科研计划科学研究重点项目(xj EDU2009I22),课题名称:bFGF基因转染的骨髓间充质干细胞复合异种煅烧骨修复颌骨缺损的实验研究 （xj EDU2009I22）
乌鲁木齐市科学技术计划项目(Y09131002),课题名称:牙周植骨术联合固定义齿夹板保留牙周炎松动牙的临床应用研究. （Y09131002）
