中国组织工程研究与临床康复2011，Vol.15Issue(20)：3759-3762,4.DOI:10.3969/j.issn.1673-8225.2011.20.036
细胞共培养在组织工程研究中的应用及价值
Application and value of cells co-culture in tissue engineering
摘要
Abstract
BACKGROUND: Cells co-culture is one kind of culture method which was established through some special culture technique in vitro. It can simulator organism intericur milieu in the greatest degree and can observe cell interaction in vitro. It is a hot topic in tissue engineering research.OBJECTIVE: To summarize and discuss the application and value of cells co-culture in the field of tissue engineering.METHODS: First author searched literatures from CNKI and Medline database from 2000 to 2010 using key words of “cells co-culture; bone marrow stem cells; neural stem cells; cartilage” both in Chinese or English. Co-culture cells were summarized from bone marrow stem cells, neural stem cells and cartilage cells in this paper. The application and value of cells co-culture in tissue engineering were also introduced.RESULTS AND CONCLUSION: A total of 182 papers were searched and 30 papers were selected. The results show that most researches of co-culture are to simulation surroundings in vivo, to maintain body character, to observe cell interaction between cells to the greatest extent. These results have significant and reference value for us; however, we should further analyze and summarize the new method and technology, pay more attention to the latest trends and hotspot of cells co-culture.关键词
细胞共培养/骨髓间充质干细胞/神经干细胞/软骨细胞/组织工程分类
医药卫生引用本文复制引用
詹兴旺,姜艳,王文良..细胞共培养在组织工程研究中的应用及价值[J].中国组织工程研究与临床康复,2011,15(20):3759-3762,4.基金项目
课题受天津市自然科学基金项目(10JCYBJC10800)资助. （10JCYBJC10800）
