中国免疫学杂志2011，Vol.27Issue(7)：607-610,4.DOI:10.3969/j.issn.1000-484X.2011.07.007
茵陈蒿汤对免疫小鼠ABO血型抗体产生的抑制作用研究
Inhibitory effect of Yinchenhao decoction on secretion of ABO antibody from immune BALB/c mouse
摘要
Abstract
0bjective :To reseach the inhibitory effect of Yinchenhao decoction on secretion of ABO antibody from immune BALB/c.Methods :After BALB/c mice were immunized with erythrocyte of A blood group, the level of IgG anti-A of BALB/c mice in immune group and therapy group was investigated with indirect antilobulin test (IAT ) ,absorption and elution test, as well as titer detection of IgG anti-A anti-body.Results:IgG anti-A of BALB/c mice in control group can not be detected while that can be detected in immune group;IgG anti-A of 5 BALB/c mice can not be detected while that can be detected in the other 11 BALB/c mice from Yinchenhao decoction therapy group .The rerults from IAT ,absorption and elution test,as well as titer detection of IgG anti-A antibody showed that the level of IgG anti-A of BALB/c mice in immune group and Yinchenhao decoction therapy group was higher than in control group ( P＜0.05 ) ,while the level of IgG anti-A in Yinchenhao decoction therapy group was lower than in immune group ( P＜0.05 ), in addition,the level of IgG anti-A in Yinchenhao decoction therapy group was no significant diffreence than in control group ( P＞0.05 ) .Conclusion :BALB/c mouse study showed that secretion of ABO antibody can be inhibited by Yinchenhao decoction therapy.关键词
茵陈蒿汤/ABO血型/抗体/分泌/效价/抑制Key words
Yinchenhao decoction /ABO blood group /Antibody /Secretion /Titer/ inhibition分类
医药卫生引用本文复制引用
周华友,于艳涛,张文,张健媛,杨贺才,刘持翔,王淑红,石文..茵陈蒿汤对免疫小鼠ABO血型抗体产生的抑制作用研究[J].中国免疫学杂志,2011,27(7):607-610,4.基金项目
本文为广东省建设中医药强省基金资助项目(2009200)和广州中医药大学创新基金资助项目(06C003) （2009200）
