首页|期刊导航|中国神经再生研究（英文版）|Effect of propofol on the reactivity of acetylcholinesterase, N-methyl-D-aspartate receptors, and gamma-aminobutyric acid receptors in the hippocampus of aged rats after chronic cerebral ischemia
中国神经再生研究（英文版）2011，Vol.6Issue(17)：1291-1295,5.DOI:10.3969/j.issn.1673-5374.2011.17.002
Effect of propofol on the reactivity of acetylcholinesterase, N-methyl-D-aspartate receptors, and gamma-aminobutyric acid receptors in the hippocampus of aged rats after chronic cerebral ischemia
Effect of propofol on the reactivity of acetylcholinesterase, N-methyl-D-aspartate receptors, and gamma-aminobutyric acid receptors in the hippocampus of aged rats after chronic cerebral ischemia
摘要
Abstract
We induced ischemic brain injury in aging rats to examine the effects of varying doses of propofol on hippocampal activities of acetylcholinesterase, N-methyl-D-aspartate receptors, and γ-aminobutyric acid receptors. Propofol exhibited no obvious impact on acetylcholinesterase activity, but directly activated the γ-aminobutyric acid receptor. The neuroprotective function of propofol on the hippocampus of aging rats following cerebral ischemic injury may be related to altered activities of γ-aminobutyric acid receptors and N-methyl-D-aspartate receptors.关键词
propofol/brain injury/acetylcholinesterase/γ-aminobutyric acid receptor/N-methyl-D- aspartate receptor/aging ratKey words
propofol/brain injury/acetylcholinesterase/γ-aminobutyric acid receptor/N-methyl-D- aspartate receptor/aging rat引用本文复制引用
Gang Chen,Jiangbei Cao,Weidong Mi..Effect of propofol on the reactivity of acetylcholinesterase, N-methyl-D-aspartate receptors, and gamma-aminobutyric acid receptors in the hippocampus of aged rats after chronic cerebral ischemia[J].中国神经再生研究（英文版）,2011,6(17):1291-1295,5.基金项目
the General Program of National Natural Science Foundation of China,No.30571791 （）
