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中枢神经系统感染160例临床分析

奚敏 胡微微 朱明芬 潘庆春 臧国庆

临床误诊误治2011,Vol.24Issue(6):32-34,3.
临床误诊误治2011,Vol.24Issue(6):32-34,3.

中枢神经系统感染160例临床分析

Clinical Analysis of 160 Patients with CNS Infection

奚敏 1胡微微 1朱明芬 1潘庆春 1臧国庆1

作者信息

  • 1. 200233,上海,上海交通大学附属第六人民医院感染科
  • 折叠

摘要

Abstract

Objective To analyze the clinical characteristics and treatment of different types of central nervous system (CNS) infection.Methods The clinical data of 160 patients with CNS infection were retrospectively analyzed.Results Among the 160 patients, 80 were viral meningitis (VM), 37 purulent encephalitis (PE), 35 tuberculous meningitis (TBM) and 8 cryptococcal meningitis (CM).All the patients received Mannitol and Glycericen and fructose for dehydration and releasing ICP and symptomatic treatment, and the treatment was effective in 148 patients.Cerebrospinal fluid (CSF) detected by lumbar puncture was normal in VM and PE patients, and it was improved significantly in TBM patients, with CSF sugar returning to normal; In CM patients, the results of India ink detection of CSF were negative for 3 times, with normal sugar and chlorine in CSF, negative result of CSF fungus culture, and significant decreasing of tire in latex agglutination test (1∶8 ~ 1∶ 320).148 patients were cured and discharged, 10 had remaining cranial nerve lesion and hydrocephalus, 12 mortalities, and fatality rate was 7.5%.Conclusion The diagnosis of CNS infection should combine clinical manifestations, CSF detection and effectiveness of the treatment.Diagnostic treatment is needed for the suspected patients with CNS infection difficult to be diagnosed at early stage to avoid missing the best treatment opportunity.

关键词

感染/中枢神经系统/病毒/结核/隐球菌属

Key words

Infection/ Central nervous system/ Viral/ Tuberculous/ Cryptococcal

分类

医药卫生

引用本文复制引用

奚敏,胡微微,朱明芬,潘庆春,臧国庆..中枢神经系统感染160例临床分析[J].临床误诊误治,2011,24(6):32-34,3.

临床误诊误治

OACSTPCD

1002-3429

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