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训练方式对大鼠空间学习、记忆的影响

司春婴 胡志红 刘恺丰 刘晓民 李雯靖

山西医科大学学报2011,Vol.42Issue(7):539-541,3.
山西医科大学学报2011,Vol.42Issue(7):539-541,3.DOI:10.3969/J.ISSN.1007-6611.2011.07.004

训练方式对大鼠空间学习、记忆的影响

Effects of training modes on spatial learning and memory in rats

司春婴 1胡志红 2刘恺丰 1刘晓民 1李雯靖1

作者信息

  • 1. 河南科技大学医学院,洛阳,471003
  • 2. 河南科技大学医学院生理教研室
  • 折叠

摘要

Abstract

Objective To explore the efFects of short-tenn reinforcing training and long-term training on spatial leaming and memory in male adult rats. Methods Sixteen healthy male adult rats were randomly divided into short-term reinforcing training group and longterm training group. In long-term training; group, four trails per arumal per day were performed for 5 days. In short-term reinforcing training group.20 trails were performed in only one day. Then long-term memory was tested at 7 d after Fmishing che training. Results During Morris water maze training,no significant difference was found in the spatial leaming ability between two groups. But the longterm memory in long-term training group was superior to that in short-term reinforcing training group( P <0. 05 ) . Conclusion Both short-term reinforcing and long-term training with the same number of trials can equally improve spatial leaming; capacity. However,only long.term tmining, but not short-term reinforcing training,can form the long-term memory.

关键词

空间学习/记忆/Morris水迷宫/训练方式

Key words

spatial leaming/ memory/ Morris water maze/ training mode

分类

医药卫生

引用本文复制引用

司春婴,胡志红,刘恺丰,刘晓民,李雯靖..训练方式对大鼠空间学习、记忆的影响[J].山西医科大学学报,2011,42(7):539-541,3.

基金项目

河南科技大学2010年大学生研究训练计划(SRTP2010172) (SRTP2010172)

山西医科大学学报

OACSTPCD

1007-6611

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