摘要
Abstract
Objective: To discuss the effect of different target concentration of remifentanil and propofol on intraocular pressure. Method: 88 patients were randomly divided into four groups. Patients in group D were anesthetized with fentanyl and propofol, and patients in group A, B, C were treated with remifentanil and propofol of different target concentration as 2μg/mL,4μg/mL,6 μg/mL. Then checked lOP, MAP, HR of the 4 groups in different time. Result: The IOP before intubation in group A, B, C were significantly lower than that in group D ( P＜0.05 ), but the data in group A, B, and C had no significant difference (P＞0.05 ). The group A IOP in 5 minutes after intubation was significantly lower than that before anesthesia ( P＜0.05 ), and it was significantly higher than that before intubation ( P＜0.05 ). The MAP and HR before intubation in group B and C were significantly lower than that before anesthesia ( P＜0.05 ), and MAP and HR in group A of 5 minutes after intubation were significantly higher than that before intubation. Conclusion:Remifentanil and propofol are the ideal clinical drugs with total intravenous anesthesia, and the target concentration of 4μg/mL or 6μg/mL has good control effect for intraocular pressure, which is suitable for clinical practice.关键词
靶浓度/瑞芬太尼/异丙酚/麻醉诱导/眼内压Key words
Target concentration/ Remifentanil/ Propofol/ Induction of anesthesia/ Intraocular pressure
