实用临床医药杂志2011,Vol.15Issue(9):71-72,83,3.
沙利度胺联合化疗治疗实体瘤疗效观察
Efficacy of Thalidomide combined with chemotherapy in the treatment of solid tumor
杨兰平 1黄汉生 1陈慧华 1傅军民 1文玲波1
作者信息
- 1. 广西省柳州市肿瘤医院,化疗科,广西,柳州,545006
- 折叠
摘要
Abstract
Objective To investigate the adjunctive effect of Thalidomide on patients with advanced cancer. Methods Sixty- three patients with pathologically confirmed advanced cancer were randomly divided into treatment group ( n = 31) and control group ( n = 32). Patients in treatment group were administered chemotherapy plus thalidomide and those in control group were administered chemotherapy only. Response rate and side effect were observed. Results The response rate in treatment group and control group were 54.8 % and 31.2 %. There were differences between two groups (P<0.05), and the side effects were not different (P >0.05). Conclusion Thalidomide combined with chemotherapy can enhance the therapeutic effect in the treatment of advanced cancer and do not improve the adverse reaction of chemotherapy.关键词
沙利度胺/癌症/晚期/化疗/辅助治疗Key words
Thalidomide/ cancer/ advanced stage/ chemotherapy/ adjunctive therapy分类
医药卫生引用本文复制引用
杨兰平,黄汉生,陈慧华,傅军民,文玲波..沙利度胺联合化疗治疗实体瘤疗效观察[J].实用临床医药杂志,2011,15(9):71-72,83,3.