现代妇产科进展2011,Vol.20Issue(5):381-384,4.
年轻子宫内膜癌患者保留卵巢的风险评估
Risk evaluation of ovarian preservation in young women with endometrial carcinoma
摘要
Abstract
Objective : The study aims to determine the possible risk factors of coexisting ovarian malignancy and to evaluate the safety of ovary-saviing; surgery and provide advice for clinical treatment and counseling. Methods :238 young women with endometrial carcinoma who were younger than 45-year-old( including 45 ) were included in this study. All the women were hospitalized for surgery in our hospital from Nov 2005 to Dec 2009. The association between the coexisting ovarian malignancy and clinical-pathological factors were analyzed retrospectively.Follow-up has been also done on those ovary-saving patients. Results : Of the 238 cases reviewed 13 (5. 5% )was diagnosed of coexisting ovarian malignance,of which 3. 4% was metastasis and 2. 1% was synchronous primary ovarian cancer. According to multivariate analysis predictors of ovarian metastasis were ranked as tumor type,cervix involvement, serum CA125 level and tumor size of ovary,while the only predictor of synchronous primary ovarian cancer was tumor size of ovary. No recurrence was discovered among the ovary-saving patients during follow-up. Conclusion:lt is very risky to preserve ovary for women with endometrial carcinoma during surgery,since 5. 5% of the women had coexisting ovarian malignancy, Extensive preoperative and surgical evaluation i8 essential for those who have strong will to save ovary. Comprehensive patient communication, informed consent and careful fellow-up are also indispensable.关键词
子宫内膜肿瘤/危险因素/保留卵巢Key words
Endometrial neoplasm/ Risk factor/ Ovary-saving分类
医药卫生引用本文复制引用
董洁,张家文..年轻子宫内膜癌患者保留卵巢的风险评估[J].现代妇产科进展,2011,20(5):381-384,4.