中华临床免疫和变态反应杂志2011，Vol.5Issue(1)：58-61,4.
间充质干细胞在系统性硬化的应用前景
Mesenchymal Stem Cells in the Therapy of Systemic Sclerosis:A New Insight
白炜 1李梦涛 1侯勇 1曾小峰1
作者信息
- 1. 中国医学科学院,北京协和医学院,北京协和医院风湿免疫科,北京,100032
- 折叠
摘要
Abstract
Mesenchymal stem cells (MSCs) mainly stay in the bone marrow and are capable of differentiating along many kind of tissues. These years, there were many researches on the using of MSCs in autoimmune diseases. Recently, it was proved that the impairment of endothelial cell differentiation from MSCs is important in the pathogenesis of systemic sclerosis (SSc). Other researches showed that there is no significant difference in many features between MSCs of SSc patients and healthy donors. Moreover, MSCs can provide support to the haematopoietic stem cells and exhibit immune suppression functions. These may provide an opportunity of MSCs being used in hematopoietic stem cell transplantation (HSCT) therapy of SSc. All of these support that MSCs could be a potential treatment for SSc.关键词
间充质干细胞/系统性硬化Key words
mesenchymal stem cells/ systemic sclerosis分类
医药卫生引用本文复制引用
白炜,李梦涛,侯勇,曾小峰..间充质干细胞在系统性硬化的应用前景[J].中华临床免疫和变态反应杂志,2011,5(1):58-61,4.
