广东牙病防治2011，Vol.19Issue(6)：288-291,4.
机械应力刺激对成牙骨质细胞骨涎蛋白mRNA表达影响的体外研究
Effects of Mechanical Stress on Expression of BSP mRNA in Cementoblasts in vitro
包丽娜 1任柏林 2黄兰 3白丁4
作者信息
- 1. 广东省口腔医院·南方医科大学附属口腔医院番禺分院,广东,广州,511400
- 2. 贵阳医学院
- 3. 重庆医科大学口腔医院
- 4. 四川大学华西口腔医院
- 折叠
摘要
Abstract
Objective To evaluate the effects of the mechanical stress on the express of the mineral associated gene BSP in cementoblast in vitro. Methods Cementoblasts OCCM30 were subjected to mechanical stress by four-points ben ding system with tension and compression stress at 2 000 μ and 4 000 μ for3 h, 6 h, 12 h, 24 h. The expression of BSP mRNA were analysed with real time quantitive RT-PCR after mechanical loading. Results BSP mRNA was suppressed by the stresses. There is a significant difference between subjects and controls ( F ＝5. 614, P ＜0.05). Conclusion Cementoblasts are sensitive to mechanical stress, and may play a role in regulating orthodontic-related root resorption or repair.关键词
成牙骨质细胞/机械应力/骨涎蛋白/牙根吸收/牙根修复Key words
Cementoblast/ Mechanical stress/ Bone sialoprotein/ Root resorption/ Root repair分类
基础医学引用本文复制引用
包丽娜,任柏林,黄兰,白丁..机械应力刺激对成牙骨质细胞骨涎蛋白mRNA表达影响的体外研究[J].广东牙病防治,2011,19(6):288-291,4.
