摘要
Abstract
Objective To analyze the clinical and pathological features of primary bile reflux gastritis (BRG). Methods Endoscopy,Helicobacter pylori (H. pylori) detection, and histopathologic examination were performed in 218 patients with primary BRG (observed group) and 236 patients with simple chronic gastritis (SCG, control group) as identified by gastroscope in order to analyze the endoscopic abnormalities, the frequency of H. pylori infection, pathological features and scores of inflammation. Results The frequency of H.pylori infection was 39.0％ (85/218) in the observed group, which was significantly lower than that in the control group [52. 1％ (123/236)]. The topographic abnormalities of the antral mucosa as detected by gastroscopy, i.e. , congestion, hemorrhagic spots, erosion were not significantly different between BRG and SCG patients (P＞0. 05). The scores ol chronic and active inflammation were higher in patients when H. pylori infection was present than in patients without H. pylori infection in both groups (P ＜ 0. 05 ). The scores ot inflammation, the detection rates of the antral intestinal metaplasia, antral atrophy and atypical hyperplasia were all higher in observed group than in control group (P＜0, 05). The incidence of lengthening of gastric pits, telangiectasis or interstitial edema in BRG patients was alsc significantly higher than those in SCG patients (P＜0. 05). Conclusions Primary BRG shows features of chemical gastritis with a higher tendency toward mucosal atrophy, intestinal metaplasia and atypical hyperplasia. Gastropic examination and biopsy should be emphasized.关键词
胃炎/胆汁返流/病理学/临床/胃镜检查Key words
gastritis/ bile reflux/ pathology, clinical/ gastroscopy分类
医药卫生
